Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Eicosapentaenoic Acid
Cell permeable. Shown to have a beneficial effect in cardiovascular diseases and inflammation. Inhibits 5-lipoxygenase and reduces thromboxane A2 production and blood viscosity.
MilliporeSigma™ Calbiochem™ Chk2 Inhibitor, PV1019
The Chk2 Inhibitor, PV1019 controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ IKK-2 Inhibitor IV
The IKK-2 Inhibitor IV, also referenced under CAS 507475-17-4, controls the biological activity of IKK-2. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ BCL6 Inhibitor, 79-6
The BCL6 Inhibitor, 79-6 controls the biological activity of BCL6. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ PIP3 Antagonist II, DM-PIT-1
The PIP3 Antagonist II, DM-PIT-1, also referenced under CAS 701947-53-7, controls the biological activity of PIP3.
Novus Biologicals™ Celastrol, IL-17A (IL-17A Inhibitor)
Used in assays to inhibit IL-17A induction
MilliporeSigma™ Calbiochem™ β-Glycerophosphate, Disodium Salt, Pentahydrate
A phosphate group donor in matrix mineralization studies that acts as a protein phosphatase inhibitor.
MilliporeSigma™ Calbiochem™ Calyculin A, Discodermia calyx
Calyculin A, CAS 101932-71-2, is a cell-permeable inhibitor of protein phosphatase 2A (IC50 = 0.5-1 nM) and protein phosphatase 1 (PP1; IC50 = 2 nM).
MilliporeSigma™ Calbiochem™ CFTR Inhibitor II, GlyH-101
CFTR Inhibitor II, GlyH-101, CAS 328541-79-3, is a cell-permeable potent, selective and reversible open-channel blocker of CFTR (Ki = 4.3 μM in CFTR-expressing FRT cells).
MilliporeSigma™ Calbiochem™ InSolution™ U0126
A potent and specific inhibitor of MEK1 and MEK2 .
MilliporeSigma™ Calbiochem™ 12/15-Lipoxygenase Inhibitor, ML351
A cell-permeable, highly potent, selective, active site directed, mixed type inhibitor of lipoxygenase-12/15 (IC50 = 200 nM for human).
MilliporeSigma™ Calbiochem™ StemSelect™ Compound E
Notch signaling suppressor
MilliporeSigma™ Calbiochem™ Dynamin Inhibitor V, 34-2
The Dynamin Inhibitor V, 34-2 controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ D,L-Sulforaphane
An isothiocyanate isolated from broccoli that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture.
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MilliporeSigma™ Calbiochem™ Caveolin-1 Scaffolding Domain Peptide, Cell-permeable
Caveolin-1 Scaffolding Domain Peptide, Cell-permeable, blocks eNOS activity and cellular NO release in vitro and reduces inflammation and tumorigenesis in vivo.