Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Protein Arginine N-Methyltransferase Inhibitor, AMI-1
The Protein Arginine N-Methyltransferase Inhibitor, AMI-1 controls the biological activity of Protein Arginine N-Methyltransferase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Pyruvate Kinase Activator
The Pyruvate Kinase Activator controls the biological activity of Pyruvate Kinase. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ Akt Activator II, SC79
Akt Activator II, SC79, CAS 305834-79-1, is a cell-permeable compound that interacts with Akt PH domain PIP3 binding pocket and makes it more susceptible to phosphorylation by upstream Kinases.
MilliporeSigma™ Calbiochem™ InSolution™ AMPK Inhibitor, Compound C·2HCl
The InSolution™ AMPK Inhibitor, Compound C·2HCl, also referenced under CAS 866405-64-3, controls the biological activity of AMPK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ AMPK Inhibitor, Compound C
AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC50 = 25.1, 148, and 234.6 nM, respectively).
MilliporeSigma™ Calbiochem™ InSolution™ LY 294002
InSolution™ LY 294002, CAS 154447-36-6, is a 10mm solution of LY 294002 (Cat. No. 440202) in DMSO. A cell-permeable, potent, reversible and specific inhibitor of PI 3-kinase (IC50 = 1.4μM).
MilliporeSigma™ Calbiochem™ RNA Polymerase I Inhibitor II, CX-5461
A cell-permeable, selective inhibitor of RNA polymerase I-mediated pre-rRNA transcription (IC50 = 142 nM in HCT-116 cells).
MilliporeSigma™ Calbiochem™ HDAC6 Inhibitor II, BRD9757
A cell-permeable, low molecular weight hydroxamate compound that acts as a potent histone deacetylase class IIb HDAC6-selective inhibitor (IC50 = 30nM), while inhibiting class I HDAC1/2/3/8 only at higher concentrations (IC50
MilliporeSigma™ Calbiochem™ AKR1C1 Inhibitor, 5-PBSA
The AKR1C1 Inhibitor, 5-PBSA, also referenced under CAS 4906-68-7, controls the biological activity of AKR1C1.
MilliporeSigma™ Calbiochem™ Aurora Kinase Inhibitor VI, ZM447439
The Aurora Kinase Inhibitor VI, ZM447439, also referenced under CAS 331771-20-1, controls the biological activity of Aurora Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ CXCR4 Antagonist I, AMD3100
The CXCR4 Antagonist I, AMD3100, also referenced under CAS 155148-31-5, controls the biological activity of CXCR4. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ NAE Inhibitor, MLN4924
NAE Inhibitor, MLN4924, CAS 951950-33-7, is an AMP mimetic that forms a NAE-catalyzed NEDD8 adduct, which acts as a tight-binding, ATP-competitive NAE inhibitor (IC50 = 4.7nM).
MilliporeSigma™ Calbiochem™ Oxymetazoline Hydrochloride
Oxymetazoline Hydrochloride is an α2-Adrenergic receptor agonist. Enhances EGF- and PDGF-induced DNA synthesis.
MilliporeSigma™ Calbiochem™ InSolution™ Trichostatin A, Streptomyces sp.
A potent and reversible inhibitor of histone deacetylase
MilliporeSigma™ Calbiochem™ Troglitazone
A α-tocopherol (vitamin E) moiety containing thiazolidinedione class of insulin-sensitizer that acts as an activator of peroxisome proliferator-activated receptors γ (PPARγ).